Immunohistochemistry

The Global Tissue Diagnostics Market overview was valued at $3,202.5 Million in 2015 and is envisaged to reach $4,471.1 Million by 2020 growing at a remarkable CAGR of about 6.9% in the forecast period of 2015 to 2020. The tissue diagnostics market heralds remarkable and affluent growth potential from 2015 with the major factor that drives the growth is the increasing ubiquity of cancer; while on the other hand, the high degree of consolidation, inflexible regulatory requirements, and dearth of budgets are exorbitating the global growth of this market. The tissue diagnostics categorized into immunohistochemistry (IHC), digital pathology, in-situ hybridization, workflow, and histo-staining. In 2015, the immunohistochemistry accounted for the largest stake in the global tissue diagnostics market with the technology segment of Tissue diagnostics mainly driven by IVD (in vitro diagnostics).

Immunohistochemistry, abbreviated as IHC is a potent method in localizing unambiguous antigens present in the Formalin Fixed, Paraffin Embedded (FFPE) tissues/ specimens predicated on the antigen–antibody interactions. The FFPE technique is extensively used in various research and diagnostics concerning dermatological and histological specimens; IHC’s applications expand continually primarily because of its convenience, reliability, and versatility. In IHC an antigen–antibody complex is explored through the light microscopy. The elementary advantage of IHC over immunofluorescence is the counterstaining which allows the visibility of the morphology of tissue around the antigen with hematoxylin. Results of stained markers are recorded semi-quantitatively and apparently have paramount diagnostic and prognostic implications for skin tumors, lymphoma, and also in the detection of infectious microorganisms in the infected specimens. IHC staining is largely used in the diagnosis of cancerous cells. IHC is also employed in studying and understanding of the distribution and localization of biomarkers and various characteristically expressed proteins in a biological tissue.

  • IHC in Association with Virology
  • Immune system response againsts viral infections
  • IHC in the diagnosis of cancerous cells
  • The distribution and localization of Biomarkers
  • IHC in cancer

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